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Retinal Vein Occlusion

Retinal vein occlusion (RVO) is blockage of a vein draining the retina. Blockage of the central vein within the optic nerve leads to Central RVO, affecting all of the retina. Blockage involving a smaller vein leads to branch RVO, which affects a portion of the retina.

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Branch RVO

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Central RVO

The blockage in the vein reduces blood flow, limiting oxygenation and nutrient supply to the affected part of the retina. The pressure in the vein also rises. This leads to dilation of the veins and leakage of serum and blood, causing retinal swelling and haemorrhage. Ultimately, the affected part of the retina can become irreversibly damaged by the lack of oxygen.

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OCT scan showing macular swelling. Fluorescein angiography (right) shows damage to blood vessels.

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Treatment of Retinal Vein Occlusion
Laser therapy is used to treat macular swelling and to prevent complications of ischaemia (damage due to lack of blood flow).

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Macular oedema

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Intraocular injections have become the main treatment of macular oedema.

 

Anti-VEGF agents are most commonly used, but steroid injections are also effective.

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Vitrectomy may be required for persistent vitreous haemorrhage or retinal scarring and detachment.

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Before Surgery

After Surgery

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